Novel MR imaging and theranostics using Nano-DDS

DOI Web Site 1 Citations 34 References
  • Aoki Ichio
    Molecular Imaging Center, National Institute of Radiological Sciences, Japan (NIRS)
  • Jo Jun-ichiro
    Department of Biomaterials, Institute for Frontier Medical Sciences, Kyoto University
  • Cabral Horacio
    Department of Bioengineering, Graduate School of Engineering, The University of Tokyo
  • Bakalova Rumiana
    Molecular Imaging Center, National Institute of Radiological Sciences, Japan (NIRS)
  • Bennett Kevin M.
    The University of Hawaii at Manoa, Department of Biology, College of Natural Sciences

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Other Title
  • ナノDDS がもたらす新しいMRイメージングとナノ・セラノスティクス
  • ナノ DDS ガ モタラス アタラシイ MR イメージング ト ナノ ・ セラノスティクス

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Abstract

Nano-DDSs have provided many improvements, such as sensitivity, multimodality, ability to respond to the environment or an external trigger, and theranostics (therapeutics and diagnostics), for preclinical magnetic resonance imaging (MRI). Nanocarriers like polymers, nano-micelle, carbon nano-materials (fullerene and carbon nanotube), and PEGylated liposome, have been investigated and the merits and limitations of each have slowly become clear. This review discusses the progress and unresolved issues for existing nano-DDSs for MRI applications, and summarizes recent work with responsive and theranostic nanocarriers.

Journal

  • Drug Delivery System

    Drug Delivery System 30 (1), 47-53, 2015

    THE JAPAN SOCIETY OF DRUG DELIVERY SYSTEM

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