Anticancer agent-incorporating immunomicelles

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  • Yamamoto Yoshiyuki
    Department of Gastroenterology and Hepatology, Institute of Clinical Medicine, University of Tsukuba
  • Hamaguchi Tetsuya
    Division of Gastrointestinal Medical Oncology, National Cancer Center Hospital
  • Matsumura Yasuhiro
    Investigative Treatment Division, Research Center for Innovative Oncology, National Cancer Center Hospital East

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Other Title
  • 抗体付加抗がん剤内包ミセル
  • コウタイ フカ コウガンザイ ナイホウ ミセル

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Abstract

Various anticancer agents-incorporating polymeric micelles, categorized as passive targeting nanoparticles are currently under clinical evaluation. On the other hand, recently, several polymeric micelles with the active targeting ability using tumor-specific antibody have been developed and exhibited the potent antitumor activity in the preclinical studies. We introduce the characteristics and developmental status of these immunoconjugates.

Journal

  • Drug Delivery System

    Drug Delivery System 30 (1), 10-15, 2015

    THE JAPAN SOCIETY OF DRUG DELIVERY SYSTEM

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