腰椎椎体における拡散尖度解析
書誌事項
- タイトル別名
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- Diffusion Kurtosis in the Vertebral Bone Marrow
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説明
To assess the structure of cancellous tissue in the vertebral bone marrow, we analyzed the restricted diffusion using diffusion kurtosis. On a 1.5T MRI, single-shot diffusion echo planar imaging was used with b values of 0, 20, 120, 500, 1200 and 2200 s/mm2, and a sensitivity encoding technique. Apparent diffusion kurtosis (Kapp) and apparent diffusion coefficient (Dapp) were calculated from diffusion kurtosis analysis based on non-Gaussian diffusion theory. Kapp and Dapp were determined in the lumbar vertebral body of seven normal subjects, and then compared with the bone mineral density (BMD) obtained with dual-energy X-ray absorptiometry. Moreover, fat fraction (FF) of the bone marrow was measured with spectral presaturation with inversion recovery in the same subject. A strong positive correlation was found between Kapp and BMD (R2 = 0.63, P = 0.034) , and FF (R2 = 0.72, P = 0.015) . However, there was no significant correlation between Dapp and BMD, and FF. These results indicating the greater utility of the Kapp than that of the Dapp. Water-restricted diffusion analysis with diffusion kurtosis makes it possible to obtain more detailed information on the structure of cancellous tissue and the bone metabolism.
収録刊行物
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- 医用画像情報学会雑誌
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医用画像情報学会雑誌 31 (1), 24-27, 2014
医用画像情報学会
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詳細情報 詳細情報について
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- CRID
- 1390282679630285696
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- NII論文ID
- 130003393069
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- ISSN
- 18804977
- 09101543
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- 本文言語コード
- ja
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- 資料種別
- journal article
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- データソース種別
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- JaLC
- CiNii Articles
- KAKEN
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- 抄録ライセンスフラグ
- 使用不可
