STUDIES ON INDUSTRIAL STYRENE POISONING (PART XIII) : Experimental Studies about the Damage on the Mucosal Membrane of Respiratory Tracts of Rats Exposed to Styrene : Contemporary Observations of the Changes in Ciliary Functions and Fine Structures

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  • 工業スチレン中毒に関する研究　ＸＩＩＩ　　ラットにおけるスチレンの気道粘膜障害に関する実験的研究　　線毛運動機能と微細構造におよぼす影響の経時的観察
  • コウギョウ スチレン チュウドク ニカンスルケンキュウ 13 ラット ニ オケ

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Abstract

Styrene is known to have an irritating effect on the tracheal mucosa, but there are few reports that have demonstrated it histologically. We carried out styrene-exposure experiments on rats, and made observations on morphological changes of the trachea with an electron-microscope. Observations on its functional aspects were also made by estimation of the cilliary movement per minute. The present study has revealed a considerable damaging effect of styrene on the tracheal mucosa, which we have presented in this report in the hope that it could be used as an index in settling the maximum permissible concentration of styrene for the future.

Journal

  • Sangyo Igaku

    Sangyo Igaku 24 (4), 360-372, 1982

    Japan Society for Occupational Health

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