Measurement of ethylene oxide at a medical sterilization site.

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  • 医療現場におけるエチレンオキシドの測定
  • イリョウ ゲンバ ニ オケル エチレンオキシド ノ ソクテイ

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Although ethylene oxide gas is widely used as a sterilizing agent for medical instruments because of its disinfection property, the effects of its use in medical settings have not been clarified. In the present study, we measured the ethylene oxide gas concentration (EOGC) within a hospital sterilization unit and in the ambient air near the unit.<br>Before the sterilizer was turned on (about 9:00), the ambient air EOGC was below the detection limit (0.1 ppm). When the door was opened to place the instruments in the sterilizer, the maximum EOGC near the door of the sterilizer was 1.71 ppm. Before the sterilizer door was opened, the residual EOGC within the sterilizer was 0.10-24.56 ppm. During the operation of the sterilizer (9:00-17:00), ethylene oxide gas could not be detected in the air near the unit. When the sterilizer door was opened at the end of the routine operation of the sterilizer (about 17:00), EOGC near the door was 2.10-2.73 ppm. After the door was closed, the ambient air EOGC level was 0.5-0.57 ppm.<br>These findings indicate that the personnel near the unit were exposed to ethylene oxide gas for about 15 min during the transfer. However, no ethylene gas could be detected by the ethylene oxide gas monitor (3M Co., #3551). The finding that EOGC in sterilized medical instruments after 24 h of aeration was about 2 ppm also suggests that the personnel using these instruments were exposed to ethylene oxide gas.<br>None of the EOGC values obtained in this study exceed the recommended threshold limit value of Japan which was revised from 50 ppm to 1 ppm in 1990. Further environmental management as well as continuous monitoring of EOGC in medical workplace settings are required, since the effect of long-term ethylene oxide gas exposure at low concentration has not yet been determined.

Journal

  • Sangyo Igaku

    Sangyo Igaku 35 (5), 413-418, 1993

    Japan Society for Occupational Health

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