Development of Probiotics for Helicobacter pyloni Infection

  • KIMURA Katsunori
    Food Functionality Research Institute Meiji Dairies Corporation
  • SAKAMOTO Ichiko
    Department of Infectious Diseases Department of Internal Medicine, Tokai University School of Medicine
  • IGARASHI Muneki
    Department of Internal Medicine, Tokai University School of Medicine
  • TAKAGI Atsushi
    Department of Internal Medicine, Tokai University School of Medicine
  • MIWA Takeshi
    Department of Internal Medicine, Tokai University School of Medicine
  • AIBA Yuji
    Department of Infectious Diseases
  • KOGA Yasuhiro
    Department of Infectious Diseases

書誌事項

タイトル別名
  • Development of Probiotics for <I>Helicobacter pyloni</I> Infection
公開日
2003
DOI
  • 10.12938/bifidus1996.22.1
公開者
財団法人 日本ビフィズス菌センター

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説明

To develop probiotics for Helicobacter pylori infection, we screened 203 Latobacillus strains. Lactobacillus gasseri OLL2716 (LG21) was selected as the most effective strain to inhibit the growth of H. pylori by in vitro tests and animal study. We examined the effects of yogurt containing LG21 on H. pylori infection in humans. The intake of yogurt containing LG21 both decreases the number of H. pylori and also reduces mucosal inflammation. LG21 was shown to be effective as a probiotic for H. pylori infection.

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