Molecular hydrogen in the treatment of acute and chronic neurological conditions: mechanisms of protection and routes of administration
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- Dohi Kenji
- Department of Emergency, Disaster and Critical Care Medicine, School of Medicine, Showa University Department of Emergency Medicine, The Jikei University School of Medicine Division of Gerontology and Geriatric Medicine, Department of Medicine, University of Washington
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- Satoh Kazue
- Department of Anatomy, School of Medicine, Showa University
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- Miyamoto Kazuyuki
- Department of Emergency, Disaster and Critical Care Medicine, School of Medicine, Showa University
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- Momma Shusuke
- Department of Emergency, Disaster and Critical Care Medicine, School of Medicine, Showa University
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- Fukuda Kenichiro
- Department of Emergency, Disaster and Critical Care Medicine, School of Medicine, Showa University
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- Higuchi Ryo
- Department of Emergency, Disaster and Critical Care Medicine, School of Medicine, Showa University
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- Ohtaki Hirokazu
- Department of Anatomy, School of Medicine, Showa University
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- A Banks Williams
- Division of Gerontology and Geriatric Medicine, Department of Medicine, University of Washington
書誌事項
- 公開日
- 2017
- 資源種別
- journal article
- DOI
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- 10.3164/jcbn.16-87
- 公開者
- 一般社団法人 日本酸化ストレス学会
この論文をさがす
説明
<p>Oxidative stress caused by reactive oxygen species is considered a major mediator of tissue and cell injuries in various neuronal conditions, including neurological emergencies and neurodegenerative diseases. Molecular hydrogen is well characterized as a scavenger of hydroxyl radicals and peroxynitrite. Recently, the neuroprotective effects of treatment with molecular hydrogen have been reported in both basic and clinical settings. Here, we review the effects of hydrogen therapy in acute neuronal conditions and neurodegenerative diseases. Hydrogen therapy administered in drinking water may be useful for the prevention of neurodegenerative diseases and for reducing the symptoms of acute neuronal conditions.</p>
収録刊行物
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- Ｊｏｕｒｎａｌ ｏｆ Ｃｌｉｎｉｃａｌ Ｂｉｏｃｈｅｍｉｓｔｒｙ ａｎｄ Ｎｕｔｒｉｔｉｏｎ
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Ｊｏｕｒｎａｌ ｏｆ Ｃｌｉｎｉｃａｌ Ｂｉｏｃｈｅｍｉｓｔｒｙ ａｎｄ Ｎｕｔｒｉｔｉｏｎ 61 (1), 1-5, 2017
一般社団法人 日本酸化ストレス学会