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- 宗像 昭子
- 昇陽会阿佐谷すずき診療所
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- 鈴木 利昭
- 昇陽会阿佐谷すずき診療所
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- 新井 浩之
- 昇陽会高円寺すずきクリニック
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- 横井 真由美
- 昇陽会阿佐谷すずき診療所
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- 深澤 篤
- 昇陽会阿佐谷すずき診療所
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- 逢坂 公一
- 昇陽会阿佐谷すずき診療所
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- 松崎 竜児
- 昇陽会阿佐谷すずき診療所
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- 三浦 明
- 昇陽会阿佐谷すずき診療所
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- 渡辺 香
- 昇陽会阿佐谷すずき診療所
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- 森薗 靖子
- 昇陽会高円寺すずきクリニック
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- 権 京子
- 昇陽会阿佐谷すずき診療所
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- 金澤 久美子
- 昇陽会阿佐谷すずき診療所
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- 宮内 郁枝
- 昇陽会阿佐谷すずき診療所
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- 鈴木 恵子
- 昇陽会高円寺すずきクリニック
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- 久保 和雄
- 昇陽会阿佐谷すずき診療所
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- 尾澤 勝良
- 昇陽会南池袋診療所
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- 前田 弘美
- 昇陽会南池袋診療所
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- 小篠 榮
- 昇陽会南池袋診療所
書誌事項
- タイトル別名
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- Analysis of kinetics of blood ionized calcium during hemodialysis using an i-STAT portable, hand-held blood analyzer.
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抄録
The present study investigated the kinetics of blood ionized calcium (i-Ca) during hemodialysis to develop a nomogram and conversion table for easy calculation of serum total calcium (T-Ca) concentration using the whole blood i-Ca concentration obtained with an i-STAT analyzer.<br>1) Fifty-nine stable ESRD patients were treated with 4-hrs regular hemodialysis treatments using the dialysate, which contained the calcium concentration of 3.0mEq/l (1.5mmol/l). 2) Serum T-Ca concentration increased significantly from 9.43±0.90 (predialysis) to 10.5±0.70mg/dl (postdialysis) (p<0.05). Whole blood i-Ca also increased from 1.26±0.10 to 1.30±0.07mmol/l (p<0.0001). 3) lonized calcium proportion (i-Ca to T-Ca concentration ratio) decreased significantly after dialysis from 53.43±0.03 to 49.55±0.04% (p<0.001). A significant inverse relationship between blood pH and the ionized calcium proportion. 4) We also investigated the relationship between serum T-Ca and whole blood i-Ca concentration before and after dialysis. In predialysis, there was a good relationship between two factors, T-Ca=7.507×i-Ca+0.015 (r=0.839; p<0.001). In postdialysis, however, there was no significant relationship noted. Finally, multiple regression analysis with other factors such as pH and albumin, was required to obtain a significant result; T-Ca=3.369×i-Ca+5.117×pH-32.070 (r=0.436; p=0.0052).<br>In conclusion, measurement of whole blood i-Ca concentration, using the i-STAT portable “point-of-care” analyzer and utilization of the normogram for estimated serum T-Ca concentration are very useful for the diagnosis and treatment of abnormal calcium metabolism in hemodialysis units.
収録刊行物
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- 日本透析医学会雑誌
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日本透析医学会雑誌 34 (13), 1525-1533, 2001
一般社団法人 日本透析医学会
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詳細情報 詳細情報について
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- CRID
- 1390282679652101120
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- NII論文ID
- 10008044195
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- NII書誌ID
- AN10432053
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- ISSN
- 1883082X
- 13403451
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
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- 抄録ライセンスフラグ
- 使用不可