透析患者の骨関節症状のｇｒａｄｅ　ｓｃｏｒｉｎｇと，各種パラメータ（ＭＤ＆ＭＤ／ＭＳ法）の検討

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  • Evaluation of microdensitometry parameters of chronic hemodialysis patients grouped by pain grade score.

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One hundred seven patients (65 males and 42 females) out of 187 patients treated by means of hemodialysis have been sampled to investigate correlations between pain grade score, bone microdensitometry (MD) parameters and blood biochemical studies. The patients were divided into the following 4 groups on the basis of pain grade score, Group 1, pain score 0; Group 2, pain score 1-7; Group 3, pain score 8-14; Group 4, pain score more than 15 points. Both age and duration of hemodialysis were greater in Group 4 than in any other pain score group. MD parameters were positively correlated with all of the pain groups. We were unable to detect any significant correlation between AI-P, or β2-MG and pain groups. C-PTH, HS-PTH and BGP (osteocalcin) levels in Group 1, the pain-free group, were higher than in any other pain score group. Parathyroidectomy (PTX) was performed in 10 cases, and with the exception of these 10 cases, serum levels of C-PTH, HS-PTH and BGP were examined, and the results were the same. The serum AI levels in Group 4 were the highest in all of the pain score groups. This suggests that long-term hemodialysis might result in low bone turnover. We conclude that MD parameters and pain grade score are useful in following ROD in long-term hemodialysis patients.

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