Comparison of the short-term outcomes of Expanded Polytetrafluoroethylene Graft (E-PTFEG) and Thoratec Vascular Access Graft (TVAG) in hemodialysis patients.

  • Otsubo Shigeru
    Division of Nephrology, Department of Medicine, Shizuoka General Hospital Department of Medicine, Kidney Center, Tokyo Women's Medical University
  • Mori Noriko
    Division of Nephrology, Department of Medicine, Shizuoka General Hospital
  • Nagai Kojiro
    Division of Nephrology, Department of Medicine, Shizuoka General Hospital
  • Matsuo Ken
    Division of Nephrology, Department of Medicine, Shizuoka General Hospital
  • Maehara Yoko
    Division of Nephrology, Department of Medicine, Shizuoka General Hospital
  • Nitta Kosaku
    Department of Medicine, Kidney Center, Tokyo Women's Medical University
  • Akiba Takashi
    Division of Blood Purification, Kidney Center, Tokyo Women's Medical University
  • Nihei Hiroshi
    Department of Medicine, Kidney Center, Tokyo Women's Medical University

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  • 血液透析患者におけるポリウレタン製人工血管(Thoratec Vascular Access Graft,TVAG)とExpanded Polytetrafluoroethylene Graft(E‐PTFEG)の早期開存率の比較

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We performed a single center study comparing Thoratec® Vascular Access Graft (TVAG) and Expanded Polytetrafluoroethylene Graft (Gore-tex® Stretch vascular grafts, E-PTFEG) with respect to the patency. Sixty-one patients (TVAG 38, E-PTFEG 23) were enrolled in this study. Gender distribution, mean age, duration of dialysis, rate of complication by diabetics or cardiovascular disease did not significantly differ between the two groups. At 6 and 12 months, primary patency rates were 75.4% and 59.2%, respectively, in the TVAG group and 73.7% and 57.3%, respectively, in the E-PTFEG group. At 6 and 12 months, secondary patency rates were 94.3% and 75.4%, respectively, in the TVAG group and 87.0% and 66.7%, respectively in the E-PTFEG group. There were no significant differences between the two groups in primary and secondary patency rates. The interval between surgery and first use of the graft was 15.1±3.8 days in TVAG and 19.9±5.0 days in E-PTFEG. TVAG could be punctured earlier than E-PTFEG (p=0.003). We concluded that graft patency of TVAG was similar to that of E-PTFEG. When dialysis patients are immunocompromised, appropriate prophylaxis of infection induced by TVAG is necessary. TVAG also has disadvantages such as frequent kinking when implanted over elbow joints.

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