A survey of constipation in dialysis patients

DOI 6 Citations 15 References Open Access
  • Nishihara Mai
    Department of Pharmacy Service, Shirasagi Hospital Department of Clinical Pharmacy and Clinical Pharmacokinetics, Osaka University of Pharmaceutical Sciences
  • Hirata Sumio
    Department of Pharmacy Service, Shirasagi Hospital
  • Izumi Satoshi
    Department of Pharmacy Service, Shirasagi Hospital
  • Furukubo Taku
    Department of Pharmacy Service, Shirasagi Hospital
  • Ota Miyuki
    Department of Pharmacy Service, Shirasagi Hospital
  • Fujita Minori
    Department of Pharmacy Service, Shirasagi Hospital
  • Yamakawa Tomoyuki
    Department of Medicine, Shirasagi Hospital
  • Tanaka Kazuhiko
    Department of Clinical Pharmacy and Clinical Pharmacokinetics, Osaka University of Pharmaceutical Sciences

Bibliographic Information

Other Title
  • 透析患者の便秘症についての実態調査

Search this article

Description

The Rome II Modular Questionnaire was used to survey 235 patients with end stage renal disease to diagnose types of coexisting intestinal diseases. These patients included 202 patients undergoing hemodialysis (HD), 33 patients undergoing continuous ambulatory peritoneal dialysis (CAPD); 147 males and 88 females; 60 diabetic patients and 175 non-diabetic patients. Patients who were diagnosed as having functional constipation by the questionnaire and patients who were users of laxatives without functional constipation were defined as having constipation. Factors related to the development of symptoms of constipation were investigated by several analytical methods.<br>Overall, 54% of subjects indicated some type of intestinal disease on the questionnaire. 19% of the patients had functional constipation, 16% had functional diarrhea, 14% had irritable bowel syndrome, 5% had functional abdominal bloating. Since 19% of the subjects had functional constipation and 33% were users of laxatives without functional constipation, 52% of patients were defined as having constipation. On chi square test, the frequency of constipation was significantly higher in females than in males, significantly higher in diabetic patients than in non-diabetic patients, and significantly higher in HD patients than in CAPD patients. When the relationship between the distribution of constipation patients and age was investigated, the frequency of constipation increased dramatically with aging. Furthermore, as factors involved in the development of constipation symptoms, aging, diabetes, and female gender were found to be significant factors on multiple logistic regression analysis. When laxative users diagnosed as having functional diarrhea were excluded from the group with constipation, the same statistical tests were carried out. The frequency of constipation did not significantly differ between diabetic and non-diabetic patients on chi square test. Factor selected for the development of constipation symptoms was only age, and diabetes was not selected on multiple logistic regression analysis.

Journal

Citations (6)*help

See more

References(15)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top