Role of relatively low sodium dialysate dialysis in maintenance hemodialysis patients with hypertension
-
- Nakayama Masaru
- Department of Internal Medicine, Kashima Hospital
-
- Ishii Atsushi
- Department of Internal Medicine, Kashima Hospital
-
- Nakano Hirofumi
- Department of Internal Medicine, Kashima Hospital
Bibliographic Information
- Other Title
-
- 高血圧合併維持透析患者における透析液ナトリウム濃度低下に伴う降圧効果とその機序に関する検討
- コウケツアツ ガッペイ イジ トウセキ カンジャ ニ オケル トウセキエキ ナトリウム ノウド テイカ ニ トモナウ コウアツ コウカ ト ソノ キジョ ニ カンスル ケントウ
Search this article
Description
Objectives : Hemodialysis (HD) using relatively low sodium dialysate (LSHD) has been used to control high blood pressure (BP). However, circulation volume-independent mechanisms of the anti-hypertensive effect have yet been not clearly elucidated. Methods : Twenty-five maintenance HD patients with hypertension underwent regular-HD for 12 weeks followed by LSHD for 12 weeks. Twenty-four-hour ambulatory blood pressure monitoring and echocardiography were performed at the end of each phase. Results : Significant decline in both systolic BP (178±17mmHg to 157±19mmHg, p<0.01) and diastolic BP (91±10mmHg to 84±11mmHg, p<0.01) were observed. Left ventricular chamber volumes did not demonstrate any significant difference between the 2 phases despite the equal dry-weight settings. The effective arterial elastance decreased with LSHD (2.07±0.75mmHg/mL to 1.65±0.49mmHg/mL, p<0.01). Conclusions : Reduced vascular resistance due to amelioration of sympathetic overactivity could be partly involved with the anti-hypertensive mechanisms of LSHD.
Journal
-
- Nihon Toseki Igakkai Zasshi
-
Nihon Toseki Igakkai Zasshi 41 (2), 133-137, 2008
The Japanese Society for Dialysis Therapy
- Tweet
Details 詳細情報について
-
- CRID
- 1390282679656006400
-
- NII Article ID
- 10021274346
-
- NII Book ID
- AN10432053
-
- ISSN
- 1883082X
- 13403451
-
- NDL BIB ID
- 9398472
-
- Text Lang
- ja
-
- Data Source
-
- JaLC
- NDL
- Crossref
- CiNii Articles
-
- Abstract License Flag
- Disallowed