Correlation between carotid parameters measured by ultrasonography and cerebral infarction or left ventricular diastolic function in chronic hemodialysis patients

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  • 慢性血液透析患者における頸動脈エコー所見と脳梗塞あるいは左室拡張能との関連性
  • マンセイ ケツエキ トウセキ カンジャ ニ オケル ケイドウミャク エコー ショケン ト ノウコウソク アルイハ サシツ カクチョウノウ ト ノ カンレンセイ

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Abstract

Many studies have reported that carotid parameters measured by ultrasonography are predictors for cerebral infarction in nondialysis patients. Using a cross-sectional design, this study investigated whether those carotid parameters are also associated with cerebral infarction and left ventricular diastolic function in chronic hemodialysis (HD) patients. We studied 63 HD patients aged 61.4±11.5 years who underwent regular hemodialysis in Hidaka Hospital. All subjects underwent carotid ultrasound measurements when they performed brain magnetic resonance imaging (MRI) or computed tomography (CT). Cerebral infarction was detected significantly more frequently in patients with max intima-media thickness of common carotid artery (IMT)>2.2mm (Odds ratio=3.14, 95%CI=1.11-8.92). There was a positive correlation between PS and E/E' (r=0.322, p=0.009). These findings suggest that max IMT is significantly associated with the presence of cerebral infarction, while PS is related to left ventricular diastolic function in chronic HD patients.

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