A patient with blood transfusion-related side effects of a fresh frozen plasma preparation used during ABO blood type-incompatible kidney transplantation

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  • Yumoto Mikiko
    Department of Anesthesiology, Tokyo Women's Medical University
  • Kume Keiko
    Department of Anesthesiology, Tokyo Women's Medical University
  • Morioka Nobutada
    Department of Anesthesiology, Tokyo Women's Medical University
  • Fuchinoue Shouhei
    Department of Surgical Nephrology, Kidney Center, Tokyo Women's Medical University
  • Kai Kotaro
    Department of Surgical Nephrology, Kidney Center, Tokyo Women's Medical University
  • Tomita Yusuke
    Department of Surgical Nephrology, Kidney Center, Tokyo Women's Medical University
  • Ozaki Makoto
    Department of Anesthesiology, Tokyo Women's Medical University

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  • ABO血液型不適合生体腎移植術中に用いた新鮮凍結血漿製剤で輸血副作用を呈した1症例
  • 症例報告 ABO血液型不適合生体腎移植術中に用いた新鮮凍結血漿製剤で輸血副作用を呈した1症例
  • ショウレイ ホウコク ABO ケツエキガタ フテキゴウ セイタイジンイショク ジュッチュウ ニ モチイタ シンセン トウケツ ケッショウ セイザイ デ ユケツ フクサヨウ オ テイシタ 1 ショウレイ

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Abstract

A 62-year-old male, in whom hemodialysis was introduced due to chronic glomerulonephritis, as a primary disease, in 2003, was admitted for kidney transplantation. Surgery was performed. A fresh frozen plasma (FFP) preparation used during surgery may have caused transfusion-related acute lung injury (TRALI), which raises an issue regarding blood transfusion-related side effects. In this patient, ABO blood type-incompatible transplantation was conducted, and a blood preparation was used during surgery. As deterioration of the respiratory state related to this preparation was observed, anesthesia control was required to maintain the transplanted kidney function while performing detailed examination of the etiology and treatment. We report this patient, and review ABO blood type-incompatible kidney transplantation, which may be increasingly performed in the future, and blood transfusion therapy.

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