Newly Designed Tensile Test System for in vitro Measurement of Mechanical Properties of Cytoskeletal Filaments

DOI 機関リポジトリ HANDLE Web Site Web Site 被引用文献2件 参考文献27件
  • DEGUCHI Shinji
    Department of Bioengineering and Robotics, Graduate School of Engineering, Tohoku University Department of Energy Systems Engineering, Graduate School of Natural Science and Technology, Okayama University
  • OHASHI Toshiro
    Department of Bioengineering and Robotics, Graduate School of Engineering, Tohoku University
  • SATO Masaaki
    Department of Bioengineering and Robotics, Graduate School of Engineering, Tohoku University

この論文をさがす

抄録

A tensile test system for isolated cytoskeletal filaments, which enables to control strain rate, was newly designed. A pair of piezo-driven cantilevers were used to manipulate the specimen and to measure tensile load from the deflection of one of the cantilevers. The displacements of the cantilevers were optically and electrically detected. The specimen strain, determined from the cantilever displacements, was used as a feedback signal. We proposed a servo-system for strain rate control in which a desired path for the strain transition was designated. The path was chosen as a triangular-shape waveform against time, along which the strain rate is kept constant. We measured tensile properties of a single stress fiber isolated from a smooth muscle cell with this system to obtain a stretching stiffness of 45nN per strain. Performance evaluation and the tensile test demonstrated that the system enabled to carry out strain rate-controlled tensile test.

収録刊行物

被引用文献 (2)*注記

もっと見る

参考文献 (27)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ