Three Cases of Squamous Cell Carcinomas Which Enlarged Rapidly with Necrotic Cavities After Bronchoscopy

Kato Taketo, Narita Kunio, Ohara Keiji

doi:10.2482/haigan.50.822

Background. The mechanism underlying cavitation in primary lung cancer has not yet been determined. We describe the mechanism of cavitation and treatment for cases complicated by inflammation with some reference to the literature. Case 1. The patient was a 70-year-old man whose chest X-ray film showed an abnormal shadow in the left hilum. Squamous cell carcinoma was diagnosed by transbronchial lung biopsy (TBLB). Cavitation occurred in the tumor and aspiration pneumonia developed. Left lower lobectomy with wedge resection of S¹⁺² was performed 7 days after TBLB. Case 2. The patient was a 60-year-old man who complained of productive cough and whose chest X-ray film showed an abnormal shadow with cavity formation in the right hilum. Squamous cell carcinoma was diagnosed by TBLB. Subsequently, blood was observed in the sputum and his fever became exacerbated. Right lower lobectomy was performed 15 days after TBLB. Case 3. The patient was a 64-year-old man whose chest X-ray film showed an abnormal shadow with cavity formation on a medical examination. Squamous cell carcinoma was diagnosed by transbronchial biopsy (TBB). Subsequently, his sputum become mucopurulent and his fever worsened. Left pneumonectomy was performed 26 days after TBB. Conclusion. In these 3 cases, cavitation occurred after bronchoscopy. Therefore, we hypothesize that the pulmonary cavities in these patients were mainly caused by ischemic necrosis and a check-valve mechanism. In addition, we consider it important to prescribe appropriate antibiotics and perform prompt surgery in cases complicated by inflammation.<br>

Three Cases of Squamous Cell Carcinomas Which Enlarged Rapidly with Necrotic Cavities After Bronchoscopy

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