A Case of Intrapulmonary Malignant Solitary Fibrous Tumor with Abnormal Uptake on FDG-PET

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  • ＦＤＧ－ＰＥＴにて異常集積を認めた，肺内ｍａｌｉｇｎａｎｔ　ｓｏｌｉｔａｒｙ　ｆｉｂｒｏｕｓ　ｔｕｍｏｒ（ＭＳＦＴ）の１例

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Background. Solitary fibrous tumor (SFT) is a neoplasm that usually involves the pleura; less frequently, it affects a host of other sites. We report an operated case of intrapulmonary malignant solitary fibrous tumor (intrapulmonary MSFT) in which FDG positron emission tomography (FDG-PET) showed abnormal uptake. Case. The patient was a 77-year-old man with a chief complaint of a growing mass lesion on chest computed tomography (CT). The CT showed a circumscribed mass in the right middle lobe (S4). FDG-PET showed abnormal uptake in the tumor with a maximal standardized uptake value (SUV (max)) of 7.35. CT-guided percutaneous needle biopsy revealed a mesenchymal tumor and didn't yield a conclusion. Based on the high SUV (max) on FDG-PET, we suspected malignant tumor and performed right middle lobectomy under video-assisted thoracoscopy. Histopathological examination showed massive proliferation of atypical spindle cells with high cellularity and more than 4 mitotic figures per 10 high-power fields. The tumor cells were immunoreactive for vimentin and CD34 but not for cytokeratin. Based on the histopathological and immunohistochemical findings, the tumor was diagnosed as MSFT. Conclusion. We reported a case of intrapulmonary MSFT with abnormal uptake on FDG-PET. Immunohistochemistry results were essential in establishing the correct diagnosis of SFT.<br>

Journal

  • Haigan

    Haigan 48 (1), 51-55, 2008

    The Japan Lung Cancer Society

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