スナネズミ唾液腺の加齢に伴う形態的変化　光学顕微鏡的，電子顕微鏡的および細胞化学的観察

DOI 被引用文献4件
  • 藤樹 亨
    長崎大学歯学部口腔外科学第一講座 長崎大学歯学部口腔解剖学第二講座

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  • Morphological changes of the effect of aging on mongolian gerbil salivary glands. Light and electron microscopic and cytochemical studies.
  • Light and electron microscopic and cytochemical studies
  • 光学顕微鏡的, 電子顕微鏡的および細胞化学的観察

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Morphological changes of aging on the salivary glands of Mongolian gerbil (from 4-month-old to 48-month-old) were investigated by means of light microscopic, electron microscopic and cytochemical methods. This study especially focused on the effect of aging on the acinar cells of parotid and submandibular glands. The most prominent changes noted in both the acinar cells of parotid and submandibular glands were ultrastructual varieties of the Golgi-complex components. In the acinar cells at 4 months after birth, a large numbers of transport vesicles were found between the rough endoplasmic reticulum and the cis side Golgi complex. However, few transport vesicles were seen in this area in the cases of aged animals. Some acinar cells of animals more than 36 months of age had distended rough endoplasmic reticulum. In these animals, some secretory granules might be fused to each other forming a large vacuole like structure occupying the whole cytoplasm of the acinar cells. In some acini of 48-month-old animals, the acinar cells contained irregular shaped secretory granules in their cytoplasm. There was an age-related increase in the number of cells characterized by dense bodies. indicating positive activity of acid phosphatase.

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