Immunopathological study of periodontal disease Localization of bacterial chondroitinase ABC and hyaluronidase in the gingiva of individuals with periodontal disease.
-
- Takeuchi Hiroshi
- Department of Oral Pathology, Gifu College of Dentistry
-
- Hori Yasunori
- Department of Oral Pathology, Gifu College of Dentistry
-
- Kanehisa Junya
- Department of Oral Pathology, Gifu College of Dentistry
-
- Ueda Masatoshi
- Department of Periodontlogy, Osaka Dental University
-
- Tani Akira
- Department of Oral Mircobiology, Osaka Dental University
-
- Sagawa Hirosuke
- Department of Oral Mircobiology, Osaka Dental University
Bibliographic Information
- Other Title
-
- 辺縁性歯周炎の免疫病理学的研究 VII 歯周炎と細菌酵素 2 炎症歯肉におけるBacterial chondroitinase ABCとHyaluronidaseについて
- Localization of bacterial chondroitinase ABC and hyaluronidase in the gingiva of individuals with periodontal disease
- 第7報歯周炎と細菌酵素 (その2) 炎症歯肉におけるbacterial chondroitinase ABCとhyaluronidaseについて
Abstract
The purpose of this investigation was to study the presence of bacteria chondroitinase ABC and basterial hyaluronidase in inflamed human gingiva by a fluorescence antibody technique. The presence of chondroitinase ABC was demonstrated in all of 30 cases and hyaluronidase was detected in 21 cases. Both enzymes existed on the surface of gingival epithelium, in the epithelium, in the subepithelial connective tissue and in the cytoplasm of phagocytes. The existence was mainly in the sulcular portion. The tissue or cells in which the enzymes localized suffered from destruction such as degenera-tive, atrophic and/or necrotic changes, and widened intercellluar spaces were also observed in the sulcular epithelium.<BR>From the above results, it was indicated that chondroitinase ABC and hyaluronidase, produced in dental plaque, penetrated from the surface of gnigival epithelium by hydrolysing acid mucopolysacchalide in the space of epithelium to supepithelial connective tissue and initiated periodontal disease.
Journal
-
- Japanese Journal of Oral Biology
-
Japanese Journal of Oral Biology 25 (2), 437-442, 1983
Japanese Association for Oral Biology
- Tweet
Details 詳細情報について
-
- CRID
- 1390282679659055104
-
- NII Article ID
- 130004001190
-
- ISSN
- 03850137
-
- Text Lang
- ja
-
- Data Source
-
- JaLC
- Crossref
- CiNii Articles
-
- Abstract License Flag
- Disallowed