Immunopathological study of periodontal disease

DOI

Bibliographic Information

Other Title
  • 辺縁性歯周炎の免疫病理学的研究 V‐3  膜透析法によるActinomyces抗原特異的免疫担当細胞の検出
  • 第5報 その (3) 膜透析法によるActinomyces抗原特異的免疫担当細胞の検出

Abstract

To detect the subpopulation or subset of immunecompetent cells which specifically react with oral bacterial antigens, it is most significant to clarify the correlation of immune reaction to periodontal diseases. But the method is very difficult because of lack of the precise technique to demonstrate cells which react with the antigens.<BR>In this study, the above problem was solved by a direct fluorescent antigen technique utilizing the membrane dialysis method. The FITC conjugation of a soluble antigen obtained from the mixture of Actinomyces naeslundii and A. viscosus showed an affinity with immunecompetent cells as small lymphocytes or plasma cells and a part of the inflammatory exudate in the inflamed human gingivae. The method was convenient and the results were high specific. Consequently, it was concluded that this membrane dialysis method was usefull for prospective serious immunopathological studies of periodontal diseases.

Journal

Details

  • CRID
    1390282679659094272
  • NII Article ID
    130004001123
  • DOI
    10.2330/joralbiosci1965.24.746
  • ISSN
    03850137
  • Text Lang
    ja
  • Data Source
    • JaLC
    • Crossref
    • CiNii Articles
  • Abstract License Flag
    Disallowed

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