Effect of Gambir Extract on Dental Plaque Formation

DOI 1 Citations 11 References
  • Shoto Makiko
    Department of Pediatric Dentistry, Hiroshima University School of Dentistry
  • Nii Noriko
    Department of Pediatric Dentistry, Hiroshima University School of Dentistry
  • Pradopo Seno
    Department of Pediatric Dentistry, Hiroshima University School of Dentistry
  • Suzuki Junji
    Department of Pediatric Dentistry, Hiroshima University School of Dentistry
  • Kozai Katsuyuki
    Department of Pediatric Dentistry, Hiroshima University School of Dentistry
  • Nagasaka Nobuo
    Department of Pediatric Dentistry, Hiroshima University School of Dentistry

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  • Gambir水抽出物の歯垢形成抑制に関する研究

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Abstract

Gambir, one of rubiaceae planted in Indonesia, is used as a favorite food and is traditionally considered as an effective protector of dental caries in Southeast Asia. A dried gambir, called catechu, containing much of catechin, one of the tannins, has been used as an astringent material for the mouth. In this study, the aqueous extract of gambir was examined for the inhibition of the synthesis of insoluble glucan (ISG) synthesis and the growth of mutans streptococci (MS)in vitro.<BR>Gambir aqueous extract inhibits ISG synthesis by glcosyltransferase in MS and it is speculated that the principal ingredient which inhibits the glcosyltransferase activity is most probably tannins.

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