低フォスファターゼ症の歯科学的検索

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  • Dental Observation of Hypophosphatasia

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A girl 2 years and 5 months old with the chief complaint of premature loosening and loss of the primary incisors, visited the Pedodontic Clinic of Iwate Medical University Dental Hospital. By laboratory examination, she was then diagnosed as having childhood hypophosphatasia.<BR>At the time of the first visit, A|A/BA|ABC had already exfoliated and other teeth were loosening.<BR>Particularly, C|C showed remarkable mobility and exposure of their roots. There was moderate gingivitis around the loosening teeth.<BR>Radiographs showed the resorption of alveolar bone and abnormally large pulp chambers in remaining tooth.<BR>The enamel was almost found to be normal.<BR>In the dentine of crowns, near their surface, there were anumber of lacunae along the outward form of dentine.<BR>Osteodentine and disorderly arrangement of dentinal tubuls were observed at the root surface. On the other hand, they were almost normal at near the pulp cavities.<BR>Cementum was found about the central area of the roots of |B and D|, which was very thin, and no cementum was found at the other area.<BR>The periodontal fiber was sparce and fragile.<BR>Therefore, we believe that the exfoliation or loosening of the primary teeth caused by their structure.<BR>For the present the parmanent tooth germ has been developing normally.

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