Cariogenicity and Anti-cariogenicity of Glucosyloligosaccaride in Experimental Dental Caries of Rats
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- Fujiwara Taku
- Department of Pedodontics, Osaka University, Faculty of Dentistry
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- Takei Tsutomu
- Department of Pedodontics, Osaka University, Faculty of Dentistry
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- Izumitani Akira
- Department of Pedodontics, Osaka University, Faculty of Dentistry
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- Ooshima Takashi
- Department of Pedodontics, Osaka University, Faculty of Dentistry
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- Sobue Shizuo
- Department of Pedodontics, Osaka University, Faculty of Dentistry
Bibliographic Information
- Other Title
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- 動物実験におけるグルコシルオリゴ糖の齲蝕抑制作用
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Abstract
The caries-inducing activity and the caries-inhibitory activity of Glucosyl-(GOS: a panose and maltose rich sugar mixture) were examined in in vivo experiments. Specific-pathogen-free rats were infected with Streptococcus mutans 6715 and fed cariogenic diet 2000 or a modified diet containing different sugars in place of 56% sucrose in diet 2000. The caries-inducing activity of GOS was one fifth of that of sucrose. The replacement of half of the diet sucrose content with GOS resulted in significant reduction of caries development. These results indicate that GOS is useful as an anti-cariogenic sucrose substitute.
Journal
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- The Japanese Journal of Pediatric Dentistry
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The Japanese Journal of Pediatric Dentistry 25 (3), 608-613, 1987
The Japanese Society of Pediatric Dentistry