Two cases of anaplastic large cell lymphoma and nodular sclerosis type Hodgkin's disease - A comparison in cytologic features of tumor cells in lymph nodes.
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- HOSAKA Naoki
- Department of Clinical Pathology, Toyooka Hospital
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- OGAWA Masaru
- Department of Laboratory, Toyooka Hospital
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- MATSUMOTO Toshio
- Department of Laboratory, Toyooka Hospital
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- OGAKI Hitomi
- Department of Laboratory, Toyooka Hospital
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- IKEHARA Susumu
- First Department of Pathology, Kansai Medical University
Bibliographic Information
- Other Title
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- Anaplastic large cell lymphomaと結節硬化型Hodgkin病の2例 リンパ節腫よう細胞像の比較
- A comparison in cytologic features of tumor cells in lymph nodes
- リンパ節腫瘍細胞像の比較
Abstract
Background: We treated 2 cases of anaplastic large cell lymphoma (ALCL) and nodular sclerosis Hodgkin's disease (NS-HD). It remains difficult to differentiate ALCL from NS-HD histopathologically without immunohistochemical techniques. We compared the cytological features of tumor cells in lymph nodes from patients using imprint cytology.<BR>Results: The following differences were found between the 2 diseases: 1) Tumor cells mutually adhered to form a mass in ALCL, whereas lacunar cells were diffuse and inflammatory cells, such as small lymphocytes, occurred in the background in NS-HD, 2) In ALCL, tumor cells were large but relatively even in site, whereas lacunar cells in NS-HD were larger and sizes varied markedly, 3) Nuclear polymorphism and hyperchromatism were more pronounced in lacunar cells. 4) In ALCL, Reed-Sternberg (RS)-like cells were observed to have 2 nuclei, whereas Hodgkin cells and RS cells in NS-HD were larger and accompanied by a perinucleolar halo, 5) Large numbers of tumor cells having a typical doughnut-shaped nucleus were detected in ALCL but hardly any in NS-HD.<BR>Conclusions: The above differences may provide valuable cytological information in the differential diagnosis of ALCL and NS-HD.
Journal
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- The Journal of the Japanese Society of Clinical Cytology
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The Journal of the Japanese Society of Clinical Cytology 40 (2), 144-148, 2001
The Japanese Society of Clinical Cytology
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Details 詳細情報について
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- CRID
- 1390282679667259776
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- NII Article ID
- 130003758834
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- ISSN
- 18827233
- 03871193
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- Text Lang
- ja
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- Data Source
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- JaLC
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed