Imprint cytology of struma ovarii-Three cases.

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  • 卵巣甲状腺腫３例の捺印細胞像

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Abstract

Background: Struma ovarii is an uncommon tumor accounting for 1-3% of ovarian teratomas and it rarely shows malignant changes, making it difficult to establish diagnostic criteria for malignancy.<BR>Cases: Three cases of struma ovarii are described, occuring in women between 37 and 47 years of age. The tumors, all unilateral, ranged from 6.5 to 7.0 cm in the greatest diameter. They all were multicystic and partially solid in one case. Imprint cytology showed thyroid follicular cells with many macrophages in the background. In one case with packed follicles, histological examination revealed struma ovarii with the features of thyroid follicular adenoma. In another case with papillary clusters showing nuclear atypia but lacking the “ground glass” or grooved nuclei, histological examination revealed struma ovarii with marked papillary formation but lacking the cytologic features required for a diagnosis of malignancy.<BR>Conclusion: Imprint cytology of struma ovarii is similar to that of the thyroid gland proper and in the case of proliferative struma ovarii, careful cytological and histological examination should be undertaken.

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