Diagnostic pitfalls on aspiration cytology of salivary gland. Cytology of salivary gland tumors. Pitfalls with squamous cells.

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Other Title
  • 唾液腺穿刺吸引細胞診のピットフォール　　唾液腺腫ようの細胞診　　へん平上皮細胞がみられる場合のピットフォール
  • pitfalls with squamous cells
  • 扁平上皮細胞がみられる場合のピットフォール

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Objective: To clarify the cytologic characteristics of squamous cells in the salivary gland, we examined aspiration and imprint cytological smears from 20 cases of salivary gland tumor.<BR>Study design: Squamous cells in cytologic smears consisting of 2 nonneoplastic lesions, 8 benign tumors, and 10 malignant tumors, were assessed for smear background, nuclear and cytoplasmic size, and features of individual cells in benign and malignant tumors.<BR>Results: (1) A necrotic background was found in malignant tumors, and frequently noted in nonneoplastic lesions and benign tumors. However, a malignant tumor of low to intermediate grade such as mucoepidermoid carcinoma (MEC) showed, a mucin background but little or no necrotic background.(2) The nuclear size of low to intermediate grade MEC was similar to that of light greenophilic metaplastic cells in pleomorphic adenomas.(3) It is important to note that high grade MEC showed atypical features with coarse chromatin and little nucleoli, while low to intermediate grade MEC showed fine chromatin and prominent nucleoli.<BR>Conclusion: Squamous cells in malignant tumors of the salivary gland featured slightly atypical features, while benign tumors showed degenerative changes. In assessign squamous cells, it is thus important to select overall cytologic features both in the background and in all cellular components.

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Details 詳細情報について

  • CRID
    1390282679668664576
  • NII Article ID
    130003758906
  • DOI
    10.5795/jjscc.41.28
  • ISSN
    18827233
    03871193
  • Text Lang
    ja
  • Data Source
    • JaLC
    • Crossref
    • CiNii Articles
  • Abstract License Flag
    Disallowed

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