A case of subependymoma of the lateral ventricle. Cytological features.

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  • 側脳室上衣下腫subependymomaの1例 その捺印細胞像
  • Cytological features
  • その捺印細胞像

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A case of subependymoma of the lateral ventricle in a 62-year-old female is reported with special emphasis of cytological features. The patient had dizziness with no other neurological symptoms and signs. Computed tomography and magnetic resonance imaging revealed a left lateral ventricular tumor, measuring 3 cm in diameter. The tumor was totally excised surgically. In smear cytology of the specimen with Papanicolou stain, sparsely distributed spindle -shaped or round tumor cells were found in a large amount of fibrillary matrix with occasional hemosiderin deposition. The tumor cells had an oval, round, or elongated and spindle -shaped nucleus with homogenous, evenly distributed fine chromatin and indistinct cytoplasm. Some tumor cell nuclei showed irregular nuclear margins. In Giemsa stained specimens, some tumor cells tended to have loose connections with each other and formed a small cluster of tumor cells. Histologically, proliferation of round tumor cells in the prominent fibrillary matrix was observed and the tumor cells were scattered or focally accumulated. Microcystic change was also recognized. A histopathological diagnosis of subependymoma was made. In conclusion, subependymoma can be differented from fibrillary astrocytoma, pilocytic astrocytoma, and schwannoma by a combination of clinical and cytological features.

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