小型円形細胞を主体とする乳癌の細胞診　乳腺硬癌の細胞学的検討　特に小型硬癌細胞を中心に

DOI

書誌事項

タイトル別名
  • Cytological Investigation of breast scirrhous carcinoma. A study of small scirrhous carcinoma cells.
  • A study of small scirrhous carcinoma cells
  • 特に小型硬癌細胞を中心に

抄録

Forty-eight cases with scirrhous carcinomas composed of small breast cancer cells, whose diagnoses had been confirmed histologically served as subjects. After being his. tologically divided according to the morphology of infiltrative lesions into trabecular type, tubular type, and solid type, the cellular characteristics of each type were examined using puncture aspiration specimens (Papanicolaou stain). In addition, the usefulness of smooth muscle actin (SMA) staining in the tubular type was also evaluated. The results obtained revealed the importance of determining the presence or absence of heterogeneous nuclei or intracytoplasmic lumina through an immersion objective for the trabecular type. Sporadic monotonous tumor cells and the presence of small solid groups without cell polarization were characteristic of the solid type. Due to its glandular arrangement with a small number of layers and the lack of remarkably atypical cells, the tubular type required differentiation from benign lesions. However, morphological infiltration (appearance of mold-like cell groups and transformation from glandular to mold-like form) was observed in-this type, providing a clue to its diagnosis. In addition, it was suggested that SMA staining is useful for diagnosing cancer with a glandular-like arrangement, if the two cell pattern of myoepithelial cells on SMA staining is taken into account with regard to the presence of myofibroblasts around the lesion.

収録刊行物

キーワード

詳細情報 詳細情報について

  • CRID
    1390282679669046528
  • NII論文ID
    130003758660
  • DOI
    10.5795/jjscc.35.640
  • ISSN
    18827233
    03871193
  • 本文言語コード
    ja
  • データソース種別
    • JaLC
    • Crossref
    • CiNii Articles
  • 抄録ライセンスフラグ
    使用不可

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