An autopsy case of malignant thymoma with pure red cell aplasia during the clinical course.

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  • 悪性胸腺腫の１剖検例　　穿刺生検細胞診による組織像の推移

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Abstract

A 42-year-old woman, who had been suffering from dysphagia, was admitted to hospital. She was diagnosed as having lymphocyte-predominant thymoma from needle aspiration biopsy of a lower mediastinal tumor. During the clinical course, pure red cell aplasia was noticed and liver metastasis was suspected on the basis of the results of roentgenography and ultrasonography. She died five years and seven months after admission due to severe generalized infection. Autopsy revealed an epithelioid cell-predominant malignant thymoma in the anterior mediastinum, but no liver involvement was noted.<BR>Intranuclear inclusions and cytomegaly were noted in the lungs, uterus-vagina, rectum, urinary bladder, tongue and tonsils. The spleen weighed 7 g and showed the features of hypoplasia histologically, which seemed to have played a part in the patient's immunocompromised state.

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