Liquid based cytologic findings of papillary squamous cell carcinoma of the vagina—A case report—
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- ADACHI Sumiyo
- Department of Surgical Pathology, Teikyo University Chiba Medical Center
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- YAMAZAKI Kazuto
- Department of Surgical Pathology, Teikyo University Chiba Medical Center
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- YAMAMOTO Yoshinari
- Department of Surgical Pathology, Teikyo University Chiba Medical Center
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- TOYONAGA Yasuhiro
- Department of Surgical Pathology, Teikyo University Chiba Medical Center
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- WATANABE Takako
- Department of Surgical Pathology, Teikyo University Chiba Medical Center
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- KOYAMA Yoshinori
- Department of Surgical Pathology, Teikyo University Chiba Medical Center
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- RYO Yoshimitu
- Department of Obstetrics and Gynecology, Teikyo University Chiba Medical Center
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- ISHIDA Yasuo
- Department of Surgical Pathology, Teikyo University Chiba Medical Center
Bibliographic Information
- Other Title
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- LBC (Liquid based cytology) 標本における腟原発乳頭状扁平上皮癌の細胞像
- Liquid based cytologic findings of papillary squamous cell carcinoma of the vagina^|^mdash;A case report^|^mdash;
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Abstract
Background : Papillary squamous cell carcinoma (PSCC) is a rare variant of the cervicovaginal carcinoma, and it is difficult to judge the presence of stromal invasion pre-operatively. We report the liquid based cytology (LBC) findings of a case of vaginal PSCC.<br>Case : A 69-year-old woman, G3P2, was referred to our hospital with the complained of a bloody vaginal discharge. Pelvic examination revealed a vaginal pednuclated mass. A cervical smear showed some characteristic features ; (1) large atypical cell clusters in a clear background, (2) the atypical cells in the clsters often showed a papillary to whorled arrangement with a fibrovascular core, (3) the atypical cells showed basaloid features with round to oval nuclei containing small nucleoli and thick cytoplasm, (4) the cell borders were not distinct, (5) single cell keratosis or koilocytosis was not observed. Histologically, the resected tumor was diagnosed as PSCC with minimal stromal invasion.<br>Conclusion : These characteristic cytological findings were more apparent in LBC preparations as compared to conventional cytology smears. LBC seems to be a useful method for detecting cervicovaginal PSCC.
Journal
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- The Journal of the Japanese Society of Clinical Cytology
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The Journal of the Japanese Society of Clinical Cytology 53 (3), 206-212, 2014
The Japanese Society of Clinical Cytology
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Details 詳細情報について
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- CRID
- 1390282679671389184
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- NII Article ID
- 130004513256
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- ISSN
- 18827233
- 03871193
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- Text Lang
- ja
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- Data Source
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- JaLC
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed