A yolk sac tumor arising in the mediastinum

DOI 9 References
  • MINAMI Tomoya
    Department of Laboratory Medicine and Radiology, Division of Pathology, Hyogo Prefectural Amagasaki Hospital
  • OGIHARA Eri
    Department of Laboratory Medicine and Radiology, Division of Pathology, Hyogo Prefectural Amagasaki Hospital
  • MATSUKI Shinichiro
    Department of Laboratory Medicine and Radiology, Division of Pathology, Hyogo Prefectural Amagasaki Hospital
  • TAKAGAKI Kazuyo
    Department of Laboratory Medicine and Radiology, Division of Pathology, Hyogo Prefectural Amagasaki Hospital
  • ISHIDA Yukari
    Department of Laboratory Medicine, Division of Pathology, Hyogo Prefectural Cancer Center
  • KOMAI Takao
    Department of Laboratory Medicine and Radiology, Division of Pathology, Hyogo Prefectural Amagasaki Hospital
  • NAKAJIMA Naoki
    Department of Surgical Pathology, Hyogo Prefectural Amagasaki Hospital
  • TAKASU Kosho
    Department of Surgical Pathology, Hyogo Prefectural Amagasaki Hospital

Bibliographic Information

Other Title
  • 縦隔に発生した卵黄嚢腫瘍の 1 例

Search this article

Description

Background : Yolk sac tumors (YST) are one of the germ cell tumors producing alpha fetoprotein (AFP) and a relatively rare gonadal tumor occurring at a young age. In the extremely rare cases, it arises in extragonadal sites. We report herein on a case of YST in the mediastinum.<br>Case : A giant mass in the left lung field was seen on chest X-ray and computed tomography (CT) imaging in a woman in her 20s. Taking the result of aspiration cytology into consideration, we suspected the presence of an undifferentiated malignant tumor. Judging from immunohistochemistry of the cell block, we diagnosed the tumor as a YST. After retrospective observation of the same aspirated specimens, we were able to identify the characteristic cytological findings of a YST such as so-called “balloon animal”-like cell clusters and hyaline globules.<br>Conclusions : Although finding “balloon animal”-like cell cluster and hyaline globules is valuable in diagnosing YST, it is difficult to identify YST from other similar diseases judging from only these cytological findings. It is very important to make the diagnosis, taking into general consideration results from other examinations, such as HE staining, cell block immunohistochemistry and clinical information.

Journal

References(9)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top