The Effects of Chlordiazepoxide on the Switch-Off Behavior Motivated by Hypothalamic Stimulation in the Cat

DOI

Bibliographic Information

Other Title
  • ネコの視床下部刺激によるスイッチ切り行動におよぼすchlordiazepoxideの影響

Abstract

The purpose of this study was to investigate the effects of chlordiazepoxide on the switch-off behavior (SOB) motivated by hypothalamic stimulation in nine tame adult cats.<BR>Chlordiazepoxide (10mg/kg) was administrated by an intramuscular injection. The response latency of SOB was measured just before the administration of chlordiazepoxide, and 30 minutes, 1 hr, 2 hrs, 3 hrs, and 24 hrs after the administration.<BR>The results were followings : <BR>1. Grooming behavior appeared about 1 hr after the administration of chlordiazepoxide and continued for about 1 hr.<BR>2. The response latency of SOB began to lengthen at about 30 minutes or 1 hr after the administration of chlordiazepoxide, and was the longest at about 2 hrs after the administration. The latency of SOB at about 24 hr after the administration of chlordiazepoxide was as long as before the administration.<BR>3. From these observations, it is considered that the locus of actions of chlordiazepoxide in the brain was the hypothalamus. In some other studies, it was reported that the locus of actions of chlordiazepoxide in the brain might be the amygdala. This disagreement could be explained by the mechanism that the amygdala might regulate the emotional responses produced by the hypothalamus.

Journal

Details 詳細情報について

  • CRID
    1390282679672095104
  • NII Article ID
    130003446250
  • DOI
    10.2502/janip1944.16.133
  • ISSN
    18836283
    00035130
  • Data Source
    • JaLC
    • Crossref
    • CiNii Articles
  • Abstract License Flag
    Disallowed

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