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Usefulness of touch imprint cytology with immunocytochemistry of sentinel lymph node metastases in breast cancer
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- UEDA Kiyofumi
- Division of Hospital Pathology, Kinki University Hospital
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- MORI Kanako
- Division of Hospital Pathology, Kinki University Hospital
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- KOBAYASHI Ayaka
- Division of Hospital Pathology, Kinki University Hospital
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- TESHIMA Yuko
- Division of Hospital Pathology, Kinki University Hospital
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- DOBASHI Chikoto
- Division of Hospital Pathology, Kinki University Hospital
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- UESUGI Tadao
- Division of Hospital Pathology, Kinki University Hospital
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- KIMURA Masatomo
- Department of Pathology, Kinki University Faculty of Medicine
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- MAENISHI Osamu
- Department of Pathology, Kinki University Faculty of Medicine
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- SATOU Takao
- Division of Hospital Pathology, Kinki University Hospital Department of Pathology, Kinki University Faculty of Medicine
Bibliographic Information
- Other Title
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- 乳癌センチネルリンパ節割面捺印標本に対する免疫細胞化学の有用性
- —Comparison with one-step nucleic acid amplification assay—
- —OSNA 法との対比—
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Description
Objective : To examine the superiority of immunocytochemistry (ICC) to Papanicolaou (Pap.) staining in touch imprint cytology for detecting sentinel lymph node metastases in patients with breast cancer.<br>Study Design : We analyzed 79 samples that were rated as positive by the One-step nucleic acid amplification (OSNA) assay. Each of the samples was sectioned serially and evaluated by touch imprint cytology with Pap. staining or ICC staining, and the results were compared with those of the OSNA assay.<br>Results : There was a statistically significant difference in the concordance rate of cytology between Pap. staining and ICC staining with the results of the OSNA assay for the detection of micrometastases (p<0.001), although there was no significant difference in the concordance rate of cytology between Pap. staining and ICC staining with the results of the OSNA assay for the detection of macrometastases.<br>Conclusion : Imprint cytology with ICC yields a significantly higher positivity rate than imprint cytology with Pap. staining. Imprint cytology with ICC is practicable for intraoperative evaluation of sentinel lymph node metastases and useful for institutions without facilities for the OSNA assay.
Journal
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- The Journal of the Japanese Society of Clinical Cytology
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The Journal of the Japanese Society of Clinical Cytology 53 (4), 280-285, 2014
The Japanese Society of Clinical Cytology
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Details 詳細情報について
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- CRID
- 1390282679672788864
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- NII Article ID
- 130004691302
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- ISSN
- 18827233
- 03871193
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- Text Lang
- ja
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- Data Source
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- JaLC
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed
