26尿中アミノアセトフェノン関連物質について
書誌事項
- タイトル別名
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- Urinary Aminoacetophenone Derivatives and Their Biosynthesis
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説明
Studies were carried out on the urinary excretion and biosynthetic pathways of aminoacetophenone derivatives.<BR>1. Administration of tryptophan to hens or rats resulted in occurrence of aminoacetophenone (AAP), 2-amino-3-hydroxyacetophenone (3 HAAP) and 2-amino- 5-hydroxyacetophenone (5 HAAP).<BR>2. Kynurenine was enzymically converted to kynurenamine by 0.01 M phosphate buffer (pH 8. 0) extract of rat liver and then non enzymically to AAP.<BR>3. 5HAAP was formed from 5-hydroxykynurenine via 5-hydroxykynurenamine by 0.01 M phosphate buffer (pH 8. 0) extract of rat small intestine through the similar route to that of formation of AAP from kynurenine.<BR>4. Rat liver rnicrosomes catalyzed hydroxylation of AAP to yield 3HAAP in the presence of NADPH.
収録刊行物
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- Proceedings of the Symposium on Chemical Physiology and Pathology
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Proceedings of the Symposium on Chemical Physiology and Pathology 11 (0), 249-252, 1972-08-25
一般社団法人 日本臨床化学会
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詳細情報 詳細情報について
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- CRID
- 1390282679673339392
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- NII論文ID
- 130003355340
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- ISSN
- 21874085
- 03863417
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可