書誌事項
- タイトル別名
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- Five cases of malignant lymphoma in the breast that could be diagnosed by the fine needle aspiration cytology
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Background: Breast malignant lymphomas (ML) are rare among breast malignant neoplasms. We here report the cytological features of five cases of breast ML.<BR>Cases: The five women ranged in age from 52 to 84 years old. The chief complaints of all the cases were breast masses, and the tumor size ranged from 2.1 to 8.7 cm. Regional lymph node metastasis was observed in one case, and the cytological features in this case showed the largest lymphoma cells among the five cases. The cytological findings of the fine needle aspiration (FNA) cytology specimens obtained in all the cases showed abundant single neoplastic cells and also revealed lymphoglandular bodies in the background. Neoplastic cells were relatively small with a high N/C ratio. The nuclei were hyperchromatic and possessed large and prominent nucleoli. Chromatin was fine and granular. Two cases showed irregular-shaped nuclei. Based on these cytological characteristics, the cytological diagnosis in all the cases was ML. The diagnosis of ML was confirmed by post-operative histological examinations, and the classification of ML was diffuse large B cell lymphoma in all five cases. A mastectomy was performed by in all the cases and followed by chemotherapy in four cases.<BR>Conclusion: The cytological diagnosis of all reported cases of breast ML has been malignant, suggesting a histological diagnosis of ML. Therefore, this report showed that FNA cytology is a valuable examination for the diagnosis of breast ML. More detailed histological subclassifications and analyses of immunohistochemical prognostic factors, such as CD5, bcl-2 and p53, are necessary for the prognostic evaluation of breast ML.
収録刊行物
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- 日本臨床細胞学会雑誌
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日本臨床細胞学会雑誌 44 (5), 298-303, 2005
公益社団法人 日本臨床細胞学会
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詳細情報 詳細情報について
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- CRID
- 1390282679673395584
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- NII論文ID
- 130003759024
- 110001868257
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- NII書誌ID
- AN00198721
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- ISSN
- 18827233
- 03871193
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
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- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可