神経鞘腫の細胞像—Antoni A 型, Antoni B 型における肉眼的・組織学的所見との比較・検討—

  • 田中 可奈子
    群馬大学医学部附属病院病理部 群馬大学大学院保健学研究科
  • 佐藤 香織
    群馬大学医学部附属病院病理部
  • 西島 良美
    群馬大学医学部附属病院病理部 群馬大学大学院保健学研究科
  • 吉田 朋美
    群馬大学大学院保健学研究科
  • 小山 徹也
    群馬大学医学部附属病院病理部 群馬大学大学院医学系研究科病理診断学
  • 福田 利夫
    群馬大学大学院保健学研究科

書誌事項

タイトル別名
  • Cytological appearances of Schwannoma—Comparison between Antoni type A and Antoni type B based on macroscopic and histological features—
公開日
2012
DOI
  • 10.5795/jjscc.51.333
公開者
公益社団法人 日本臨床細胞学会

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説明

Objective : Schwannomas occur frequently among benign soft tissue tumors and demonstrate a variety of histological findings. An accurate understanding of the cytological features of the Schwannoma is therefore important. In this study, the cytological features of the Schwannoma were investigated comparing Antoni types A and B using imprint, squash and thin-layer specimens along with the macroscopic and histological features.<br>Study Design : Nine cases of Schwannomas arising in soft tissue were studied. Imprint, squash and thin-layer specimens were made from the fresh cut surface of resected tumors and subjected to Pap staining.<br>Results : In type A (2 cases), nuclear palisading and Verocay bodies were observed. In type B (7 cases), typical features were absent and secondary changes such as edematous/myxoid change, hemorrhage, hemosiderin deposit and macrophages were observed in 5 of the 7 cases.<br>Conclusion : Although cytological diagnosis is easy in cases with typical arrangement of the tumor cells, it is important to think of type B in cases with only the features associated with secondary changes. The combination of characteristic features from imprint, squash and thin-layer specimens can help to achieve accurate cytological diagnosis.

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