A case of Ewing sarcoma/primitive neuroectodermal tumor of the uterine cervix

DOI 2 References

Bibliographic Information

Other Title
  • 子宮頸部原発 Ewing sarcoma/primitive neuroectodermal tumor の 1 例
  • —捺印細胞像と LBC 細胞像の比較—
  • —Comparison between stamp cytology and liquid-based cytology—

Search this article

Abstract

Background : We report a rare case of Ewing sarcoma/primitive neuroectodermal tumor (ES/PNET), assumed to arise from the uterine cervix.<br>Case : A 30-year-old woman presented to us with the complaint excessive menstrual and irregular vaginal bleeding. A surgically excised specimen suggested the diagnosis of ES/PNET, both histologically and immunohistochemically. Stamp cytology revealed a large number of atypical small round cells, scattered or in focal clusters, with a high N/C ratio, hyperchromatic nuclei, a fine to coarse granular chromatic pattern and small nucleoli. Rosette-like structures were identified in parts of the clusters, suggesting neuroectodermal differentiation. However, almost all atypical cells from the LBC specimen had a fine chromatic pattern, and showed a different pattern from that of the stamp cytology.<br>Conclusion : The granular chromatic pattern is important for suspecting neuroectodermal or neuroendocrine differentiation. The tumor cells may lack the characteristic chromatic pattern, especially when processed for LBC. A liquid-based material is available for immunocytochemical staining, and by careful evaluation of the cytological and immunocytochemical findings, the correct differential diagnosis can be reached.

Journal

References(2)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top