Productivity of Bioactive Compounds in Streptomyces Species Isolated from Nagasaki Marine Environments.

DOI Web Site 参考文献29件
  • Nakashima Takuji
    NITE Biotechnology Development Center (NBDC), National Institute of Technology and Evaluation (NITE) Kitasato Institute for Life Scieneces, Kitasato University OP Bio Factory Co., Ltd.
  • Anzai Kozue
    NITE Biotechnology Development Center (NBDC), National Institute of Technology and Evaluation (NITE)
  • Suzuki Rieko
    NITE Biotechnology Development Center (NBDC), National Institute of Technology and Evaluation (NITE)
  • Kuwahara Natsumi
    NITE Biotechnology Development Center (NBDC), National Institute of Technology and Evaluation (NITE)
  • Takeshita Satoshi
    Joint Research Center, Nagasaki University
  • Kanamoto Akihiko
    OP Bio Factory Co., Ltd.
  • Ando Katsuhiko
    NITE Biotechnology Development Center (NBDC), National Institute of Technology and Evaluation (NITE)

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Based on a Blast search of 16S rRNA sequences of Streptomyces from marine environments of Nagasaki, Japan, 64 isolates showed the highest similarity scores with NBRC strains. Only 5 out of these 64 strains showed exactly the same biological profiles as the approximately 900 strains preserved at NBRC strains, while the remaining isolates showed different biological profiles. This suggests that the genus Streptomyces has the ability to produce a wide variety of unknown bioactive metabolites.

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