Immunohistochemical Detection of Lipopolysaccharide in Gram-negative Bacterial Infection

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  • グラム陰性菌感染症におけるリポ多糖抗原の免疫組織化学的検出
  • グラム インセイキン カンセンショウ ニ オケル リポ タトウ コウゲン ノ

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Abstract

Detection of a common antigen of Gram-negative bacteria was attempted with immunohistochemistry on formalin fixed paraffin sections. An anti-lipopolysaccharide (LPS) rabbit serum widely reacted with gramnegative bacterial antigens in the lesions. In addition, the anti-LPS serum was reactive with the bacterial antigens in the cytoplasm of infiltrated macrophages and giant cells in fibrous tissues where the species specific antisera were not reactive.

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