A Case of Bovine Cutaneous Lymphosarcoma

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  • 皮膚型牛白血病の1例
  • ヒフガタ ウシ ハッケツビョウ ノ 1レイ

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Abstract

A 3-years-old Holstein-Friesian dairy cow with skin leukosis was autopsied at 20 days after detection of skin lesions. Biochemical examination showed the elevation of LDH activities and α1-acid glycoprotein concentration. Antibody against bovine leukosis virus as negative and white blood cell count was 19, 400/μl with 93% lymphoid cells. Cutaneous tumors were seen almost on the whole body, and the surface and pelvic lymph nodes were remarkably enlarged. A white tumor mass in the peritoneum and a red-brown nodule on the urinary bladder mucosa were also observed. Microscopically, the epidermis showed slight hyperkeratosis. Lymphoid cells were remarkably proliferated in the dermis, and they were characterized by a round nucleus and basophilic or clear cytoplasm. Mitosis was frequent. Basophilic cells were proliferated in the perivascular areas.

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