Clinical Effects of Human Erythropoietin on Renal Anemia in Cats

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  • 猫の腎性貧血に対する人エリスロポイエチン製剤の応用
  • ネコ ノ ジンセイ ヒンケツ ニ タイスル ジン エリスロポイエチン セイザイ

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Two cats with chronic renal failure involving renal anemia were successfully treated with human erythropoietin (r-EPO). Intravenous (I.V.) administration of r-EPO at a dose of 100 IU/kg twice a week markedly increased the PCV, RBC, and Hb values. Furthermore, the comparatively favorable hematological condition was maintained for the following 25-85 weeks by continuation of the I.V. administration of r-EPO at a dose of 50-100 IU/kg once a week or every other week. The cats showed alleviation in clinical symptoms as well as an improved appetite, gaining of weight, and a glossier coat, as the anemia improved. No adverse effects were observed due to the long-term, I.V. administration of r-EPO.

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