Immune Treatment of Flea Allergic Dermatitis of Dogs with Flea Extract

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  • HAYASAKI Mineo
    School of Veterinary Medicine, Tokyo University of Agriculture and Technology
  • AKIYAMA Yuhko
    School of Veterinary Medicine, Tokyo University of Agriculture and Technology
  • KONNO Katsuhiko
    School of Veterinary Medicine, Tokyo University of Agriculture and Technology
  • OHISHI Isamu
    School of Veterinary Medicine, Tokyo University of Agriculture and Technology

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Other Title
  • 自家調製ノミアレルゲンによるノミアレルギー性皮膚炎の減感作療法
  • 自家調整ノミアレルゲンによるノミアレルギー性皮膚炎の減感作療法
  • ジカ チョウセイ ノミアレルゲン ニ ヨル ノミ アレルギーセイ ヒフエン ノ

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Description

Nine dogs with flea allergic dermatitis diagnosed by immediate-type intradermal test, were injected with a self-made allergen, which was prepared from the whole flea by ultrasonication, filtration and incubation at 65°C. Nine dogs were subcutaneously injected with 1ml of a 1: 5, 000 (W/V) dilution of the allergen once a week. Six and 3 dogs received 12 or more and 4 injections, respectively. Six (66.7%) of 9 dogs responded to the treatment with a mean improvement rate of 73%(33-100%). Slight increases in indirect hemagglutination titers were demonstrated in 3 dogs, whereas 2 dogs showed decreases in Prausnits-Kustner titers after the treatment.

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