Effect of Thiamphenicol on Bovine Bacterial Respiratory Disease

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  • KATOH Toshihide
    Veterinary Clinical Training Center, Yamagata Prefectual Federation of Agricultural Mutual Aid Associations
  • SAKAI Jun-ichi
    Veterinary Clinical Training Center, Yamagata Prefectual Federation of Agricultural Mutual Aid Associations
  • OGATA Yoshimi
    山形県農業共済連置賜家畜診療所
  • ABE Sakae
    山形県農業共済連中央家畜診療所
  • KIMURA Makoto
    (株) エーザイ・アニメイト事業部

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  • 牛の細菌性呼吸器病に対するチアンフェニコールの効果
  • ウシ ノ サイキンセイ コキュウキビョウ ニ タイスル チアンフェニコール ノ

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Effect of watersoluble thiamphenicol (TP), VII-65, for bovine bacterial respiratory disease was examined, as compared with that of ABPC. TP was administered at 10mg/kg (16 cases), 20mg/kg (25 cases), or 30mg/kg (26 cases) for 3 successive days, and ABPC was at 10mg/kg (16 cases). Temperature was improved significantly (P<0.001 or 0.01) in the all groups, but respiratory rate, vigor and appetite were not improved significantly in ABPC group, and recovery rate in the TP group was higher. From the nasal swabs Pasteurella multocida and Mycoplasma bovis were isolated from in 14 of 27 (51.9%) and 5 of 27 (18.5%) samples, respectively. The P. multocida isolates were highly susceptible to TP and ABPC, but no M. bovis isolate was sensitive to ABPC.

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