Effects of a New Vermifuge Milbemycin Oxime on Intestinal Parasites of Dogs

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  • 犬腸内寄生虫に対するミルベマイシン・オキシムの駆虫効果
  • イヌ チョウナイ キセイチュウ ニ タイスル ミルベマイシン オキシム ノ

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Using 41 verminal egg-positive dogs, the vermifugal effects of Milbem cin Oxime granules (Sankyo Co., Ltd.) were examined. Following medication at dosage levels of 0.1 and 0.2 g/kg, determination was made of the number of vermins discharged, negativity rate of verminal eggs, the number of residual vermins, general conditions of health and hematological changes between before and after medication. Dogs parasitized with Trichuris vulpis and Ancylostoma caninum from among those that were mono-parasitic discharged vermins 1-4 days following medication, with a gradual decrease in the number of eggs and finally, residual vermins could hardly be detected. Verminfugal effects were greater at 0.2g/kg compared to 0.1g/kg. Dogs parasitized with Toxocara canis discharged vermins1-3 days following medication regardless of the dosage levels; egg count became negative and there was no residual vermins. Vermifugal effects similar to those noted on mono-parasitic dogs were observed for compound parasitic dogs in that vermin-discharge condition was Virtually the same as that of mono-parasitic dogs. About 86% of 14 microfilaria-positive dogs became negative 4 days following medication. Hematological change before and after medication differed acccording to the dog but not on whether the animal was mono-parasitism (trichuriasis, ancylostomiasis or ascariasis) or compound parasitism. General health conditions were normal following medication.

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