The Effects of Adoptive Transfer of Immunity to <I>Theileria sergenti</I> Infection in Cattle
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- KOYAMA HIROYUKI
- Department of Veterinary Infectious Diseases, Kitasato University
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- NAGAI YUKIKO
- 農林水産省家畜衛生試験場東北支場
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- OGASAWARA TOSHIMI
- Department of Veterinary Infectious Diseases, Kitasato University
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- HOHDATSU TSUTOMU
- Department of Veterinary Infectious Diseases, Kitasato University
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- SAITHO HIROSHI
- Department of Veterinary Infectious Diseases, Kitasato University
Bibliographic Information
- Other Title
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- Theileria sergenti感染牛に対する耐過牛白血球の移入効果
- Theileria sergenti カンセン ウシ ニ タイスル タイカ ウ
- The Effects of Adoptive Transfer of Immunity to Theileria sergenti Infection in Cattle
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Description
Transfusion with neutrophils of cattle recovered from Theileria sergenti (TS) infection was performed to examine the effects on the percentage of parasitized erythrocytes (PPE) in peripheral blood of TS infected cattle. A cow recovered from an artificial infection with the Fukushima strain of TS showing the persistent low PPE was selected as a donor.<BR>Leukocytes were obtained from 1 liter of a donor cow's blood and washed 3 times with a buffer solution by centrifugation. These leukocytes (more than 109 cells) were intravenously injected twice to the recipient cows at 3-day intervals. PPE in recipient cows rapidly decreased, but increased again to the previous value within a few days. The leukocyte transfusion was more effective when injected 5 times. However, the neutrophils from cattle not infected with TS showed no effects on PPE in the recipient cattle. Culture supernatant of co-culture with neutrophils from the donor cow recovered from TS infection and parasitized erythrocytes from the recipient cow was injected 8 times demonstrating no effects on PPE in the recipient cow. The PPE in the recipient cow was rapidly decreased after the blood transfusion from the donor cow as was the neutrophil transfusion.<BR>These results suggested that the neutrophils of cows recovered from TS infection were effective to reduce the PPE in the cows highly infected with TS.
Journal
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- Journal of the Japan Veterinary Medical Association
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Journal of the Japan Veterinary Medical Association 41 (9), 640-644, 1988
Japan Veterinary Medical Association
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Details 詳細情報について
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- CRID
- 1390282679686383360
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- NII Article ID
- 130003847778
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- NII Book ID
- AN00191857
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- ISSN
- 21860211
- 04466454
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- NDL BIB ID
- 3211787
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- Data Source
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- JaLC
- IRDB
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed