Reproductive Examination and Histopathological Findings of Somatic Cell-Cloned Holstein Friesian Cows with Low Reproductive and Low Lactational Performance
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- TAKAHASHI Masahiro
- Technical Research Center, Koiwai Noboku Co., Ltd
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- TSUCHIYA Hideki
- (社) 家畜改良事業団家畜バイテクセンター
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- UEKI Atsushi
- Technical Research Center, Koiwai Noboku Co., Ltd
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- MITA Noriko
- Technical Research Center, Koiwai Noboku Co., Ltd
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- KUBO Masanori
- (独) 農業・生物系特定産業技術研究機構動物衛生研究所疫学研究部
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- GORYO Masanobu
- 岩手大学農学部
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- HASHIZUME Tsutomu
- 岩手大学農学部
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- OSAWA Takeshi
- 岩手大学農学部
Bibliographic Information
- Other Title
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- 繁殖性と産乳性が低いホルスタイン種体細胞クローン牛の臨床所見ならびに病理所見
- ハンショクセイ ト サンニュウセイ ガ ヒクイ ホルスタインシュ タイサイボウ クローンギュウ ノ リンショウ ショケン ナラビニ ビョウリ ショケン
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Abstract
Two somatic cell-cloned Holstein Friesian cows (Cody 1 and Cody 2) diagnosed as having low reproductive or low lactational performance were examined. Although AI or ET was performed 15 times, Cody 1 became pregnant only twice, ultimately miscarrying. Given these results, the animal was euthanized at the age of 61 months. Cody 2 calved twice with a calving interval of 690 days. In both cows, GnRH analog (fertirelin acetate, 100μg/head) was injected intramuscularly to test the ability of LH release from the pituitary, and the LH responses were similar to those of the two control cows. Macroscopically, the uterus in Cody 1 was discolored and hypoplastic, and light microscopy disclosed that there were many calcareous deposits on the wall of some uterine arteries as well as an increased number of arteries in the endometrium. In Cody 2, milk composition was normal, whereas milk yields at primiparity (3, 897kg/305days) and secondary parity (6, 312kg/305days) were much lower than those (average 11, 015kg/305days) of the somatic cell-donor cow. These results indicate the possibility that certain somatic cell-cloned cows may have low reproductive performance and low milk production.
Journal
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- Journal of the Japan Veterinary Medical Association
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Journal of the Japan Veterinary Medical Association 59 (8), 540-543, 2006
Japan Veterinary Medical Association
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Keywords
Details 詳細情報について
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- CRID
- 1390282679688008832
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- NII Article ID
- 10017643380
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- NII Book ID
- AN00191857
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- ISSN
- 21860211
- 04466454
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- NDL BIB ID
- 8063687
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- Data Source
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- JaLC
- IRDB
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed