Treatment with Febantel Combination Drug for Canine <I>Strongyloides</I> sp. Infection

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  • ITOH Naoyuki
    First Department of Small Animal Internal Medicine, Kitasato University, School of Veterinary Medicine
  • MURAOKA Noboru
  • KAWAMATA Jun
  • AOKI Mikiko
    First Department of Small Animal Internal Medicine, Kitasato University, School of Veterinary Medicine
  • ITAGAKI Tadashi
    First Department of Small Animal Internal Medicine, Kitasato University, School of Veterinary Medicine

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Other Title
  • 犬の<I>Strongyloides</I> sp. 感染症例に対するフェバンテル配合剤の治療効果
  • 犬のStrongyloides sp.感染症例に対するフェバンテル配合剤治療効果
  • イヌ ノ Strongyloides sp カンセン ショウレイ ニ タイスル フェバンテル ハイゴウザイ チリョウ コウカ
  • Treatment with Febantel Combination Drug for Canine Strongyloides sp. Infection

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The efficacy of febantel combination drug treatment was evaluated in clinical cases of dogs infected withStrongyloides sp. A single oral dose of febantel at 15 mg/kg of body weight was only 50.0%(2/4) effective ineradicating first-stage larvae of Strongyloides sp. in the feces.A second administration of the same dose failedto improve in the efficacy.In contrast, oral administration of febantel at a dose of 15 mg/kg of body weightonce daily for three connective days was 63.6%(7/11) effective against Strongyloides sp. infection in dogs.Asecond administration of the same dose in non-effective cases for three connective days was 50%(2/4) effective, giving a total efficacy of this protocol of 81.8%(9/11).

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