Spontaneous <i>Staphylococcus aureus </i>Infection with Keratitis and Leg Alopecia in <i>Chinchilla laniger </i>and Their Treatment

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  • KAWASUMI Koh
    Laboratory of Experimental Animal Science, Nippon Veterinary and Life Science University
  • SHISHIDO Mao
    ㈱メルシャンクリンテック
  • AMAO Hiromi
    Laboratory of Experimental Animal Science, Nippon Veterinary and Life Science University

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Other Title
  • チンチラの黄色ブドウ球菌性角膜炎および脚部脱毛症とその治療
  • チンチラ ノ オウショク ブドウ キュウキンセイ カクマクエン オヨビ キャクブ ダツモウショウ ト ソノ チリョウ

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Spontaneous keratitis and alopecia were detected respectively in 2 of 17 chinchillas (Chinchilla laniger) that had been bred in our laboratory. Staphylococcus aureus was isolated as a pure culture from each lesion. The isolates were sensitive to ofloxacin. After instillation of a new quinolone and a drug for the treatment of cornea ulcers five times per day for five days, followed by administration of vitamin B2 and the cornea ulcer drug twice daily for 34 days, one chinchilla, which exhibited keratitis, was completely cured. The other chinchilla, which had alopecia on the leg, was completely cured by treatment with a liniment of the new quinolone once a day for four days. S. aureus was not detected in any of the cured lesions. The data demonstrated that keratitis and alopecia on the leg can be caused by spontaneous S. aureus infection in the chinchilla, and that the treatment described here is effective against this bacterium.

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