Prediction of the Development of Fatty Liver using Lecithin

SHIBANO Kenichi, INOUE Masasuke, YAMASHIRO Yukio, ONISHI Masami

doi:10.12935/jvma1951.58.815

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Other Title

乾乳牛のレシチンコレステロールアシルトランスフェラーゼ活性値を用いた脂肪肝発生予察
カンニュウギュウノレシチンコレステロールアシルトランスフェラーゼカッセイチオモチイタシボウカンハッセイヨサツ
Cholesterol Acyltransferase Activities in Dairy Cows in the Dry Period

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Abstract

A prediction of the development of fatty liver during the peri-parturient period was performed by LCAT during the dry period in Holstein dairy cows. LCAT, FFA, BHBA, TCho, FCho, ChoE, Glu, AST and GGT in blood samples were measured and BCS was evaluated eight times during the final two weeks before calving and for three months after calving using 16 high-BCS dry cows in Trial-1. These 16 cows were divided into two groups based on the incidence of severe fatty liver. A comparison between the two groups revealed that, in the fatty liver group LCAT, TCho, FCho and ChoE were significantly lower than in the non-fatty liver group during the dry period (P<0.01). The parameters of prediction were obtained from LCAT and TCho levels during the final seven to 14 days before calving, were 830IU and 110mg/dl, respectively. In Trial-2, a prediction of the development of fatty liver was performed by the parameters obtained from Trial-1, using 32 dry cows. As a result, the odds ratios of LCAT and TCho in 32 cows from which blood samples were taken during the final seven to 25 days before calving were 7.4 and 2.3, respectively. Consequently, a prediction of the development of fatty liver can be performed using LCAT activity during the final one to three weeks before calving with higher probability.

Journal

Journal of the Japan Veterinary Medical Association

Journal of the Japan Veterinary Medical Association 58 (12), 815-819, 2005

Japan Veterinary Medical Association

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