The Reported First Case of Canine <i>Anaplasma phagocytophilum</i> Infection in Japan

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  • 犬における<i>Anaplasma phagocytophilum</i>感染症の本邦初の症例報告
  • 犬におけるAnaplasma phagocytophilum感染症の本邦初の症例報告
  • イヌ ニ オケル Anaplasma phagocytophilum カンセンショウ ノ ホンポウ ハツ ノ ショウレイ ホウコク

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Anaplasma phagocytophilum is one of the etiological agents of tick-borne rickettsial diseases. It is known as human and animal granulocytic anaplasmosis. A three-year-old neutered Shih Tzu with no history of overseas travel became anorexic and feverish one week after being bitten by a tick. The most relevant clinicopathological findings were thrombocytopenia, neutropenia, and high levels of liver enzyme activity and CRP. The antibody for A. phagocytophilum was weakly positive in the serum, and PCR analysis confirmed the diagnosis of A. phagocytophilum infection. Treatment with doxycycline was successful in resolving the clinical signs of thrombocytopenia and neutropenia. This represents the first documented case of canine A. phagocytophilum infection to be reported in Japan.

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